Syrup manufacturers in India typically makes their syrups have greater control over product quality. Traditional cough composites are based on syrup that contains 65-75% fructose, dextrose, glycogen, inverted syrup, and other ingredients. The rest consists of thickening agents, stabilizers, and active substances.
What is syrup?
Syrup is an almost saturated solution of sugar in water, such as sucrose, with or without meditative or flavoring ingredients. Medicated syrup is a syrup that has medicinal substances added to it. Flavored syrup is a non-medicinal syrup that contains flavoring substances and is used as a flavoring vehicle. It is critical that the sucrose concentration approaches but does not reach the saturated point.
Key Points
- Many of the approved syrups contain no preservatives other than a sufficient sucrose concentration.
- Sucrose concentration is a crucial factor in mold growth inhibition.
- When stored properly, nearly saturated sucrose solutions do not require a preservative. Because these remedies do not contain free water, they are hydrate medium for microorganism growth.
- Preservatives may be present in some syrups.
- If the sucrose concentration is less than 85% w/v, a sealant should be added.
Functions of Syrup Making
Any pharmaceutical syrup manufacturer in India will go through these functions. Several functions must be fulfilled by the manufacturing process:
- The sugar is dissolved to prepare the syrup.
- After that Powder ingredient hydration
- Then combines ingredients with different viscosities
- Active ingredient suspension or dissolution
- The final result must be smooth, and homogeneous.
- When purchasing equipment, GMP norms should be followed.
Issues in using convention mixer
- Using traditional provocateurs for this procedure raises several concerns:
- At room temp., conventional provocateurs cannot disintegrate high concentrations of sugars.
- The combination needs to be warmed to aid in the solution. This is not worth the time or cost.
- The further cooling process increases both expenses and processing times.
- During the heating/cooling process, the syrup may form crystals.
- Heat has the potential to harm active ingredients.
- Toughening additives will form agglomerates that will be difficult to discard with conventional equipment.
Uses of syrups
- Antibiotics, antihistaminics, antitussives, and vitamins are all delivered via syrups. The reducing sugars formed in the syrup as a result of inversion, dextrose, and levulose, are useful in slowing the oxidative stress of other substances.
- Concentrated sugars solutions inhibit the development of bacteria, fungi, and molds that cause decay of vegetable-derived drugs; this action is due to the high osmolarity pressure exerted by sucrose solution, which inhibits the development of bacteria, fungi, and molds that cause decomposition. Because they comprise little or no alcohol, they are preferable to alcoholic vehicle elixirs for children.
- They have excellent saline drug masking abilities. Because they do not contain alcohol, they are superior as cleaning agents for water-soluble substances.
- It is also used to add flavor to foods like fruits and baked products. It is typically drizzled or used as a glaze over desserts.
Lastly, many syrups like Suave Healthcare inhibit the cough reflex, and you can get rid of your cough. Expectorants help to thin mucus. It may assist your cough in clearing gunk from your airway. Drinking plenty of fluids also aids in keeping your mucus thin.